Global Market for Treatment and Diagnosis of Sexually Transmitted Diseases to Witness an Outstanding Growth by 2019 - 2023

Researchmoz added Most up-to-date research on "Global Market for Treatment and Diagnosis of Sexually Transmitted Diseases to Witness an Outstanding Growth by 2019 - 2023" to its huge collection of research reports.

Global Market for Treatment and Diagnosis of Sexually Transmitted Diseases

Sexually transmitted infections are asymptomatic and often undiagnosed. Routinely screening and preventive measures are important for early identification, which can prevent severe complications and further transmission. An untreated STD results in several other chronic diseases including pelvic inflammatory disease (PID), infertility, increased risk of HIV and other STDs. There are certain strains of HPV that are linked to cervical, penile, throat and anal cancers. Various types of STDs include:
- Gonorrhea.
- Syphilis.
- Herpes.
- Chlamydia.
- Hepatitis (HBV).
- Human Immunodeficiency Virus (HIV).
- Human Papilloma Virus (HPV or genital warts).
- Chancroid.
- Trichomoniasis.

Sexually transmitted infections are spread through sexual contact. These infections are primarily transmitted from one person to another via sexually transmissible bacteria, viruses and parasites. There are several STDs that can be transmitted through tissue transfer, blood products and from mother to child during childbirth or pregnancy. The disease symptoms vary from one person to another; in a few cases there might be no disease symptoms. Symptoms can be mild or acute from one individual to another. There can be severe consequences or long-term complications in individuals suffering from the disease.

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1888947

A significant proportion of sexually transmitted diseases worldwide is caused by eight major infections: syphilis, chlamydia, gonorrhea, genital herpes, hepatitis B, human papillomavirus (HPV) and trichomoniasis. These diseases have a high prevalence, particularly in developing countries, and it can result in substantial productivity losses for individuals, and communities. In developing countries, sexually transmitted infections are among the leading causes of disability."

"Report Scope
This report organizes information from diverse sources into a comprehensive report that includes sections on disease overviews, industry structure, diagnostic kits, treatment interventions, pharmaceutical products, emerging technologies, regulations, reimbursement and patents. The scope of this report includes an overview of the global market scenario for diagnosis and treatments of sexually transmitted disease with base year data of 2017, estimations for 2018 and forecast for 2019-2023 using projections of CAGR. Market data in value terms is provided at global, regional and country levels for disease areas and treatment by drug class. Market data for sexually transmitted disease diagnostics is provided for regional levels, with details on test types. 

Browse TOC @ https://www.researchmoz.us/global-markets-for-treatment-and-diagnosis-of-sexually-transmitted-diseases-report.html/toc

The report focuses on key sectional assessments for major disease areas such as chlamydia, genital herpes, HIV and hepatitis, among others, and provides detailed analysis of epidemiology, historic and current disease incidence trends, therapeutic interventions and diagnostic overview. It forecasts the global market by drug class for treatment of STDs and discusses market data for antibiotics, antivirals/antiretrovirals and other treatments. Diagnostic test types such as enzyme immunoassays (EIA) and ELISA, PCR, rapid diagnostics and others, are detailed with market data current and forecasts. 

Market dynamics such as drivers, restraints and trends are discussed in the report. This report also involves regional market overviews for North America, Europe, Asia-Pacific, Latin America and the Middle East. The regional overviews provide information on the epidemiology of sexually transmitted disease by country and region and also details market data for each region. The regulatory scenario is discussed for United States, Europe, Japan and China to provide an overview of the regulations for new drug launches and diagnostic kits. The reimbursement scenario is outlined for the United States, Europe, and Japan to provide an overview to our readers. Pipeline analysis and scenarios are discussed for major disease to provide details on the major pipeline developments. The competitive landscape discusses the major manufacturers involved in the sexually transmitted disease therapeutics market, key developments and product offerings.

Report Includes
- 45 data tables and 53 additional tables
- An overview of the global market for diagnosis and treatments of sexually transmitted diseases
- Country specific data and analysis for United States, Canada, Mexico, France, Germany, U.K., Spain, China, India, Japan, and Middle East and Africa
- Coverage of major disease areas, and a detailed analysis of historic and current disease incidence trends
- Discussion about market dynamics such as drivers, restraints, and trends
- Information on the regulations for new drug launches and diagnostic kits for United States, Europe, Japan and China 
- Detailed profiles of the major market players, including Abbott Laboratories, AbbVie Inc., Agilent Technologies, Inc., Biomerieux, Inc., Bio-Rad Laboratories Inc., Novartis Ag, Pfizer Inc., Promega Corp., and Thermo Fisher Scientific, Inc."

New Study On Seasonal Influenza: Competitive Landscape to 2026

Researchmoz added Most up-to-date research on "New Study On Seasonal Influenza: Competitive Landscape to 2026" to its huge collection of research reports.

Seasonal Influenza

Influenza, often referred to as the flu, is an acute infection caused by one of the three closely related viruses designated as influenza types A, B, and C. The influenza A H1N1 and H3N2, and influenza B strains are those responsible for seasonal influenza infections. 

The symptoms of influenza are similar to those of the common cold, though they are usually more severe, have a sudden onset, last for one to two weeks, and are normally self-limiting without medical treatment. The very young, elderly, and patients with chronic illness such as diabetes, asthma, or cardiovascular disease are most at risk of complications due to influenza.

This report provides an assessment of the pipeline, clinical, and commercial landscape of seasonal influenza. Overall, GlobalData expects new drug approvals to drive a shift in the treatment and prophylaxis of seasonal influenza over the next decade (2016-2026).

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1956811

Scope
This report combines data from the Pharma Intelligence Center with in-house analyst expertise to provide a competitive assessment of the disease marketplace. Components of the slide deck include - 
- Pipeline Assessment: regional breakdown, promising late-stage products, early-stage pipeline by product type
- Clinical Trials Assessment: trial breakdown by phase, leading industry and non-industry sponsors, enrollment analytics
- Commercial Assessment: leading marketed products, current and future players
- Competitive Landscape Analysis: key market events (2016-2026).

Browse TOC @ https://www.researchmoz.us/seasonal-influenza-competitive-landscape-to-2026-report.html/toc

Reasons to buy
- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
- Develop business strategies by understanding the trends shaping and driving the global seasonal influenza market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global seasonal influenza market in the future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Alzheimers Disease and Associated Indications - Exceptional Level of First-in-Class Innovation within AD, and Diverse Range of Therapies in Development for Disorders Such as Anxiety and Depression

Researchmoz added Most up-to-date research on "Alzheimers Disease and Associated Indications - Exceptional Level of First-in-Class Innovation within AD, and Diverse Range of Therapies in Development for Disorders Such as Anxiety and Depression" to its huge collection of research reports.

Alzheimer’s disease (AD), the most common form of dementia, is a progressive, neurodegenerative and currently incurable disease characterized by loss of memory and other mental abilities. It has a devastating impact on independence and quality of life, with patients requiring full-time care in the later disease stages. In addition to cognitive impairment, AD is associated with behavioral and psychological changes, which often represent the greatest challenges for patients and caregivers.

The prevalence of AD is escalating rapidly, largely owing to aging populations, as advancing age is the most important epidemiological risk factor for the disease. This will amplify the already substantial societal and economic costs of the disease over the coming years. This has led to high levels of R&D investment over the past two decades, but clinical trial failure rates within the indication are extremely high and treatment options remain limited. There are no disease-modifying therapies for AD, and current approaches can only temporarily slow the worsening of symptoms.

The report focuses on AD alongside four key associated behavioral and psychological indications: anxiety, depression, psychosis and insomnia. These four conditions are highly prevalent in AD and contribute substantially to the disease burden.

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1135804

Scope

Unmet need is extremely high in AD, with behavioral and psychological complications contributing significantly to the disease burden

• What are the most important etiological risk factors and pathophysiological processes implicated in AD? 
• What is the current treatment algorithm? 
• How common are anxiety, depression, psychosis and insomnia in AD? 

Browse TOC @ https://www.researchmoz.us/frontier-pharma-alzheimers-disease-and-associated-indications-exceptional-level-of-firstinclass-innovation-within-ad-and-diverse-range-of-therapies-in-development-for-disorders-such-as-anxiety-and-depression-report.html/toc

The AD pipeline is large and contains a very high proportion of first-in-class product innovation

• Which molecule types and molecular targets are most prominent across AD and its associated indications? 
• What are the connections, in terms of first-in-class innovation, between AD and its associated indications?
• Which first-in-class targets are most promising? 
• How does the level of first-in-class innovation differ between products in development for anxiety, depression, psychosis and insomnia? 
• How does first-in-class target diversity differ by stage of development and molecular target class?

The deals landscape is active and dominated by G-protein coupled receptor (GPCR)-targeting products

• Which indications attract the highest deal values? 
• How has deal activity fluctuated over the past decade? 
• Which first-in-class pipeline products have no prior involvement in licensing or co-development deals?

Reasons to buy

This report will allow you to - 

• Appreciate the current clinical and commercial landscapes by considering disease pathogenesis, etiology, epidemiology, symptoms, diagnosis and treatment options. 
• Identify leading products and key unmet needs within the market. 
• Recognize innovative pipeline trends by analyzing therapies by stage of development, molecule type and molecular target. 
• Assess the therapeutic potential of first-in-class targets. Using proprietary matrix assessments, first-in-class targets in the pipeline have been assessed and ranked according to clinical potential. Individual matrix assessments are provided for targets identified in the pipeline for AD, anxiety, depression, psychosis and insomnia. Promising early-stage first-in-class targets are reviewed in greater detail. 
• Consider first-in-class pipeline products with no prior involvement in licensing and co-development deals that may represent potential investment opportunities.

Overview of Global Lysosomal Disease Treatments Market | Astellas Pharma, Astrazeneca, Eli Lilly and Co., Merck & Co., Inc., and Novo Nordisk A/S

Researchmoz added Most up-to-date research on "Overview of Global Lysosomal Disease Treatments Market | Astellas Pharma, Astrazeneca, Eli Lilly and Co., Merck & Co., Inc., and Novo Nordisk A/S" to its huge collection of research reports.

Lysosomal storage diseases are a rare group of genetic disorders that resulted from the malfunctioning or lack of lysosomal enzymes. Tay-Sachs disease was the first lysosomal storage disorder (LSD). It was described in 1881 and was followed by Gaucher disease in 1882. The lysosomal storage diseases (LSD) are a group of 50 diseases that are characterized by accumulation of waste product in the lysosomes. They are rare, inborn defects and have a combined incidence rate of 1 in 1,500 to 7,000 live births. In lysosomal storage diseases there is deficiency of 1 or more of themany catabolic enzymes that are located within the lysosome. Many of the diseases known today were described even before the discovery of lysosomes. The last decade has witnessed major advances in our understanding of the clinical, biochemical and genetical aspects of lysosomal storage diseases.

The major drivers influencing the market are orphan drug status; this is a major driver of the market. Increasing awareness, rising focus by pharmaceutical companies and early diagnosis as well as newborn screening are the other drivers. The market also faces a few restraints that include expensive drugs, change in payer policies, lack of proper training and knowledge, nature of disease and concerns in diagnosis. Restraints are overcome by the drugs that aid in improving the lifespan and quality of life for the patients.

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1901583

U.S. is the major market for lysosomal storage disease treatment. It was the first country to implement orphan drug status and to provide many incentives for orphan drugs for treating rare diseases. Europe is the second-largest market; it also stands by the Orphan Drug Act. Asia-Pacific is showing the highest growth rate during the forecasted period. In China and India, the market is limited due to the high prices of the drugs.

The lysosomal storage diseases market is a subset of the larger orphan drugs market and is impacted by any change in regulation and policy on orphan drugs. There is an increasing focus on LSD as there are efficient diagnostic systems to detect greater numbers of patients. The market for Lysosomal storage diseases is estimated to reach a value of nearly REDACTED in 2018 and is expected to grow at a compound annual growth rate (CAGR) of REDACTED to nearly REDACTED by 2023. Themarket for Lysosomalstorage diseases is a concentrated market with many large players present in the market. Major players in themarket are Sanofi, Pfizer, Shi re and others."

Browse TOC @ https://www.researchmoz.us/lysosomal-disease-treatments-technologies-and-global-markets-report.html/toc

"Report Scope:
The lysosomal storage disease treatment market has been divided by type of indication into: Gauchers Diseases, Fabry Diseases, Pompes Syndrome, Mucopolysaccharidosis and more. Mucopolysaccharidosis is further segmented into Hunter syndrome, Hurlers Syndrome and Moriquo syndrome. The market is also segmented by routing of administration into IV and oral. The market has been divided into hospitals, clinics and other facilities into end users by type of treatment into enzyme replacement therapy and substrate reduction therapy. The market has been segmented into North America, Europe, Asia-Pacific and RoW.

Report Includes:
- 37 data tables and 25 additional tables
- An overview of the global market for lysosomal disease treatments
- Analyses of global market trends, with data from 2017, estimates for 2018 and projections of compound annual growth rates (CAGRs) through 2023
- Segmentation of the global market by cancer therapy indiscation, treatment type, route of administration, end-use, application and geographical region
- Information on current regulatory environment, and a trend analysis of recent government policies and regulations for lysosomal disease treatments
- Assessment of lysosomal storage diseases by the accumulated substrate and the profitability of focusing on ultra-orphan diseases
- Profiles of major players in the industry, including Astellas Pharma, Astrazeneca, Eli Lilly and Co., Merck & Co., Inc., and Novo Nordisk A/S"

Global Sickle Cell Disease Treatment Market Growth Analysis By Manufacturers - AstraZeneca Plc., Eli Lilly and Company, Bristol-Myers Squibb Company and Novartis AG

Researchmoz added Most up-to-date research on "Global Sickle Cell Disease Treatment Market Growth Analysis By Manufacturers - AstraZeneca Plc., Eli Lilly and Company, Bristol-Myers Squibb Company and Novartis AG" to its huge collection of research reports.

Persistence Market Research has come up with a new report titled “Sickle Cell Disease Treatment Market: Global Industry Analysis (2012-2016) and Forecast (2017-2025),” for the projected period of 8-years. According to this report, weighted average selling price has been considered to estimate the market size of various drugs mentioned in the scope of the study. We have not only captured the country price with the local currency but also the local currency figures is converted to USD to offer forecasts in a consistent currency standard. Furthermore, we have also considered the latest annual exchange rate to reflect the impact of the most recent economic conditions of country. Prices considered in the models are standardized based on the average dosage used per Sickle cell disease treatment per dosage in a year. Availability of branded off-patent equivalents have been taken into consideration while calculating prices.

We have used following parameters to estimate the global market size

Market sizing is done using our in-house epidemiology data based model to estimate sickle cell disease treatment market. We adopt bottom-up approach to forecast sickle cell disease treatment market globally. The following parameters are used to estimate the market size for the base year 2016:

• Country level data for prevalence and incidence rate for calculating base population
• Diagnosis rate
• Treatment rate and percentage adoption of currently available treatment options in various stages of the disease for calculating target population
• Average cost of drug treatment cycle associated with the each treatment option
• Average cost of each cycle is then multiplied by average number of cycles taken by patients for all drug type (differs from drug to drug) in an year

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1396733

We have used a number of sources to present a detailed analysis of the global sickle cell disease treatment market

Our research methodology uses both primary and secondary research to collect the relevant data. We have analyzed the market by considering the revenue through extensive primary research to understand the usage pattern, historic trends, and problems faced by the physicians, the required treatment developments, and most preferred drugs. Key opinion leaders were considered for the primary research that included experienced healthcare professionals in various healthcare facilities at country level. These estimates were further validated with drug manufacturers, distributors, and suppliers.

Extensive secondary research has been carried out to understand the epidemiology of sickle cell disease, treatment rate, adoption rate, regulatory scenarios, average selling price, reimbursement scenario, by referring published scientific literature from various databases such as the WHO, National Heart, Lung, and Blood Institute (NHLBI), PubMed, Springer, and Wiley among many others. We have also analyzed various companies’ annual report, investor presentation, SEC filings, 10k reports and press release operating in sickle cell disease treatment market to fetch substantial information about the market size, trends, opportunity, drivers, and restraints to analyze key players.

Browse TOC @ https://www.researchmoz.us/global-market-study-on-sickle-cell-disease-treatment-sickle-cell-anaemia-anticipated-to-be-the-most-lucrative-disease-type-segment-through-2025-report.html/toc

Report Inclusions and Exclusions

In this report, we have considered only those drugs that are administered for sickle cell disease treatment. The study includes drugs such as hydroxyurea, antibiotics, pain-relieving medications and others. The drugs considered in others segments are drugs that are administered based on patients conditions and also includes the newly FDA approved drug L-Glutamine for sickle cell disease treatment.

We have not included other therapies such as surgeries, blood transfusions, gene therapies and bone marrow transplantation etc. to calculate market value in this study. The market also do not includes any products from the drug type segment administered to patients of any other indications. The market value is calculated based on only the drug type (Hydroxyurea, Antibiotics, Pain-relieving medications, and other drugs) administered for sickle cell disease treatment.

Forecast Assumptions and Limitations

To forecast the market we have considered the following assumptions:

• Growth in diagnosis and treatment rate
• Change in price of drugs
• Adoption curve for available treatment
• Impact of launch of new combination regimen which are in late stage of development
• Forecasting has been done on a static base and only currently approved products have been taken into consideration for calculating the actual size of the treatment market

Our clients should note that these are the partial steps that are being followed while developing the market size. Besides this, forecasting is done on our internal proprietary model which also uses different macro-economic factors and industry based demand driving factors that are impacting the market and its forecast trends apart from disease related factors.

Global Sickle Cell Disease Treatment Market by Top Key Players Profiled: AstraZeneca Plc., Eli Lilly and Company, Bristol-Myers Squibb Company and Novartis AG

Researchmoz added Most up-to-date research on "Global Sickle Cell Disease Treatment Market by Top Key Players Profiled: AstraZeneca Plc., Eli Lilly and Company, Bristol-Myers Squibb Company and Novartis AG" to its huge collection of research reports.

Persistence Market Research has come up with a new report titled “Sickle Cell Disease Treatment Market: Global Industry Analysis (2012-2016) and Forecast (2017-2025),” for the projected period of 8-years. According to this report, weighted average selling price has been considered to estimate the market size of various drugs mentioned in the scope of the study. We have not only captured the country price with the local currency but also the local currency figures is converted to USD to offer forecasts in a consistent currency standard. Furthermore, we have also considered the latest annual exchange rate to reflect the impact of the most recent economic conditions of country. Prices considered in the models are standardized based on the average dosage used per Sickle cell disease treatment per dosage in a year. Availability of branded off-patent equivalents have been taken into consideration while calculating prices.

We have used following parameters to estimate the global market size

Market sizing is done using our in-house epidemiology data based model to estimate sickle cell disease treatment market. We adopt bottom-up approach to forecast sickle cell disease treatment market globally. The following parameters are used to estimate the market size for the base year 2016:

• Country level data for prevalence and incidence rate for calculating base population
• Diagnosis rate
• Treatment rate and percentage adoption of currently available treatment options in various stages of the disease for calculating target population
• Average cost of drug treatment cycle associated with the each treatment option
• Average cost of each cycle is then multiplied by average number of cycles taken by patients for all drug type (differs from drug to drug) in an year

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1396733

We have used a number of sources to present a detailed analysis of the global sickle cell disease treatment market

Our research methodology uses both primary and secondary research to collect the relevant data. We have analyzed the market by considering the revenue through extensive primary research to understand the usage pattern, historic trends, and problems faced by the physicians, the required treatment developments, and most preferred drugs. Key opinion leaders were considered for the primary research that included experienced healthcare professionals in various healthcare facilities at country level. These estimates were further validated with drug manufacturers, distributors, and suppliers.

Extensive secondary research has been carried out to understand the epidemiology of sickle cell disease, treatment rate, adoption rate, regulatory scenarios, average selling price, reimbursement scenario, by referring published scientific literature from various databases such as the WHO, National Heart, Lung, and Blood Institute (NHLBI), PubMed, Springer, and Wiley among many others. We have also analyzed various companies’ annual report, investor presentation, SEC filings, 10k reports and press release operating in sickle cell disease treatment market to fetch substantial information about the market size, trends, opportunity, drivers, and restraints to analyze key players.

Browse TOC @ https://www.researchmoz.us/global-market-study-on-sickle-cell-disease-treatment-sickle-cell-anaemia-anticipated-to-be-the-most-lucrative-disease-type-segment-through-2025-report.html/toc

Report Inclusions and Exclusions

In this report, we have considered only those drugs that are administered for sickle cell disease treatment. The study includes drugs such as hydroxyurea, antibiotics, pain-relieving medications and others. The drugs considered in others segments are drugs that are administered based on patients conditions and also includes the newly FDA approved drug L-Glutamine for sickle cell disease treatment.

We have not included other therapies such as surgeries, blood transfusions, gene therapies and bone marrow transplantation etc. to calculate market value in this study. The market also do not includes any products from the drug type segment administered to patients of any other indications. The market value is calculated based on only the drug type (Hydroxyurea, Antibiotics, Pain-relieving medications, and other drugs) administered for sickle cell disease treatment.

Forecast Assumptions and Limitations

To forecast the market we have considered the following assumptions:

• Growth in diagnosis and treatment rate
• Change in price of drugs
• Adoption curve for available treatment
• Impact of launch of new combination regimen which are in late stage of development
• Forecasting has been done on a static base and only currently approved products have been taken into consideration for calculating the actual size of the treatment market

Our clients should note that these are the partial steps that are being followed while developing the market size. Besides this, forecasting is done on our internal proprietary model which also uses different macro-economic factors and industry based demand driving factors that are impacting the market and its forecast trends apart from disease related factors.

Orphan and Rare Dermatological Diseases - First-in-Class Therapies Demonstrate Potential Disease-Modifying Effects in Areas of High Unmet Need Such as Epidermolysis Bullosa

Researchmoz added Most up-to-date research on "Orphan and Rare Dermatological Diseases - First-in-Class Therapies Demonstrate Potential Disease-Modifying Effects in Areas of High Unmet Need Such as Epidermolysis Bullosa" to its huge collection of research reports.

Orphan and rare dermatological diseases are considerably diverse in terms of pathophysiology, clinical presentation and disease severity. Many of these conditions are extremely debilitating and can even be life-threatening in some cases.

Disease visibility can also have a profoundly negative impact on patient confidence. Unmet need within the orphan and rare dermatology market is extremely high with some diseases having no effective treatments. The market is highly genericized and dominated to a large extent by products acting on hormones and their receptors.

Most of these are corticosteroids and are used for symptom management with no disease-modifying effects. There is a significant unmet need for more efficacious disease-modifying treatments and safer treatment options across orphan and rare dermatological diseases, as physicians often cite poor efficacy, low patient compliance and problematic safety profiles as issues associated with the long-term use of available treatments.

This report covers all orphan and rare dermatology disorders, but there is a particular focus on six key indications, systemic sclerosis (scleroderma), alopecia, epidermolysis bullosa (EB), pemphigus vulgaris, vitiligo and cutaneous lupus erythematosus (CLE), as these conditions have the largest pipelines within the therapy area.

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1918257

Scope

• There is a strong need for innovative new therapies across the orphan and rare dermatology market. How are orphan and rare dermatological diseases currently managed? What are the greatest unmet needs within this market?
• There are 262 pipeline products in development across all orphan and rare dermatological diseases. How does the composition of the pipeline compare with that of the existing market? Which molecular targets are most frequently acted upon by pipeline drugs? How do products in development for the key indications differ in terms of molecule type?
• Over one-third of pipeline products with a disclosed molecular target are first-in-class. How does the proportion of first-in-class products in development differ in terms of stage of development, molecule type and molecular target class? Which are the most promising first-in-class targets?
• The deals landscape has become more active in recent years. Which indications and products have attracted the highest deal values?

Browse TOC @ https://www.researchmoz.us/frontier-pharma-orphan-and-rare-dermatological-diseases-firstinclass-therapies-demonstrate-potential-diseasemodifying-effects-in-areas-of-high-unmet-need-such-as-epidermolysis-bullosa-report.html/toc

Reasons to buy

This report will allow you to:

• Appreciate the current clinical and commercial landscapes by considering disease pathogenesis, etiology, epidemiology, symptoms, diagnosis and treatment options.
• Visualize the composition of the market in terms of dominant molecule types and molecular targets, highlighting what the current unmet needs are and how they can be addressed. This knowledge allows a competitive understanding of gaps in the current market.
• Recognize innovative pipeline trends by analyzing therapies by stage of development, molecule type and molecular target.
• Assess the therapeutic potential of first-in-class molecular targets. Using a proprietary matrix, first-in-class targets have been assessed and ranked according to clinical potential. Promising first-in-class targets have been reviewed in greater detail.
• Consider first-in-class pipeline products with no prior involvement in licensing and co-development deals that may represent potential investment opportunities.

Global Sickle Cell Disease Treatment Market: Sickle Cell Anaemia Anticipated to be the Most Lucrative Disease Type Segment Through 2025

Researchmoz added Most up-to-date research on "Global Sickle Cell Disease Treatment Market: Sickle Cell Anaemia Anticipated to be the Most Lucrative Disease Type Segment Through 2025" to its huge collection of research reports.

Persistence Market Research has come up with a new report titled “Sickle Cell Disease Treatment Market: Global Industry Analysis (2012-2016) and Forecast (2017-2025),” for the projected period of 8-years. According to this report, weighted average selling price has been considered to estimate the market size of various drugs mentioned in the scope of the study. We have not only captured the country price with the local currency but also the local currency figures is converted to USD to offer forecasts in a consistent currency standard. Furthermore, we have also considered the latest annual exchange rate to reflect the impact of the most recent economic conditions of country.

Prices considered in the models are standardized based on the average dosage used per Sickle cell disease treatment per dosage in a year. Availability of branded off-patent equivalents have been taken into consideration while calculating prices.

We have used following parameters to estimate the global market size
Market sizing is done using our in-house epidemiology data based model to estimate sickle cell disease treatment market. We adopt bottom-up approach to forecast sickle cell disease treatment market globally. The following parameters are used to estimate the market size for the base year 2016:

• Country level data for prevalence and incidence rate for calculating base population
• Diagnosis rate
• Treatment rate and percentage adoption of currently available treatment options in various stages of the disease for calculating target population
• Average cost of drug treatment cycle associated with the each treatment option
• Average cost of each cycle is then multiplied by average number of cycles taken by patients for all drug type (differs from drug to drug) in an year

To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1396733

We have used a number of sources to present a detailed analysis of the global sickle cell disease treatment market
Our research methodology uses both primary and secondary research to collect the relevant data. We have analyzed the market by considering the revenue through extensive primary research to understand the usage pattern, historic trends, and problems faced by the physicians, the required treatment developments, and most preferred drugs. Key opinion leaders were considered for the primary research that included experienced healthcare professionals in various healthcare facilities at country level. These estimates were further validated with drug manufacturers, distributors, and suppliers.

Extensive secondary research has been carried out to understand the epidemiology of sickle cell disease, treatment rate, adoption rate, regulatory scenarios, average selling price, reimbursement scenario, by referring published scientific literature from various databases such as the WHO, National Heart, Lung, and Blood Institute (NHLBI), PubMed, Springer, and Wiley among many others. We have also analyzed various companies’ annual report, investor presentation, SEC filings, 10k reports and press release operating in sickle cell disease treatment market to fetch substantial information about the market size, trends, opportunity, drivers, and restraints to analyze key players.

Browse TOC @ https://www.researchmoz.us/global-market-study-on-sickle-cell-disease-treatment-sickle-cell-anaemia-anticipated-to-be-the-most-lucrative-disease-type-segment-through-2025-report.html/toc

Report Inclusions and Exclusions
In this report, we have considered only those drugs that are administered for sickle cell disease treatment. The study includes drugs such as hydroxyurea, antibiotics, pain-relieving medications and others. The drugs considered in others segments are drugs that are administered based on patients conditions and also includes the newly FDA approved drug L-Glutamine for sickle cell disease treatment.

We have not included other therapies such as surgeries, blood transfusions, gene therapies and bone marrow transplantation etc. to calculate market value in this study. The market also do not includes any products from the drug type segment administered to patients of any other indications. The market value is calculated based on only the drug type (Hydroxyurea, Antibiotics, Pain-relieving medications, and other drugs) administered for sickle cell disease treatment.

Forecast Assumptions and Limitations
To forecast the market we have considered the following assumptions:

• Growth in diagnosis and treatment rate
• Change in price of drugs
• Adoption curve for available treatment
• Impact of launch of new combination regimen which are in late stage of development
• Forecasting has been done on a static base and only currently approved products have been taken into consideration for calculating the actual size of the treatment market

Our clients should note that these are the partial steps that are being followed while developing the market size. Besides this, forecasting is done on our internal proprietary model which also uses different macro-economic factors and industry based demand driving factors that are impacting the market and its forecast trends apart from disease related factors.

Peripheral Artery Disease Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast

Researchmoz added Most up-to-date research on "Peripheral Artery Disease Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast" to its huge collection of research reports.

Peripheral Artery Disease (PAD) is a medical condition in which plaque builds up on the artery walls, blocking the flow of oxygen-rich blood to the legs, stomach, and arms. Major factors causing PAD are smoking, diabetes, high blood pressure, abnormal cholesterol levels, advancing age and a personal history of vascular disease. The earliest symptom of Peripheral Artery Disease is a cramp-like muscular discomfort called intermittent claudication, while numbness, tingling, weakness or fatigue is also experienced. Patients with severe PAD often develop ulcers in their legs and feet. Its prevention involves a lifelong program involving certain lifestyle changes like healthy eating and physical exercise.

Medical Diagnosis of PAD includes methods like Ankle-Brachial Index, Ultrasound, Angiography, Catheter Angiography and Blood Tests. There are a number of treatment options for the disease that can be used alone or mixed with other devices. They are Percutaneous Trans Luminal Angioplasty (PTA), Drug-Coated Balloons, Stents, Drug-Eluting Stents, Arterial Bypass and Atherectomy.
The global peripheral artery disease market, bolstered by rising healthcare expenditures has seen a persistent growth in the last few years. The report provides an overview of the entire global peripheral artery disease market including the devices market and the atherectomy market. Certain key trends like increased used of DCBs and favorable reimbursements have also been discussed. Growth drivers including rising ageing population, obesity and healthcare expenditures find mention in the report along with the challenges and limitations including underpenetrated treatment market for PAD.

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Competition in the global peripheral artery disease market is rather fragmented with big companies recording excellent profits while smaller companies continue to gain prevalence through research and innovation.

The report has forecasted future trend in the global Peripheral Artery Disease market by combining SPSS Inc.’s data integration and analysis capabilities. Regression models have been created by employing various significant variables that have an impact on the market. Before deploying the regression model, the relationship between several independent or predictor variables and the dependent variable was analyzed using standard SPSS output, including charts, tables, and tests.

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Table of Content

1. Market Overview 
1.1 Introduction
1.2 Causes of Peripheral Artery Disease
1.3 Prevention
1.4 Diagnosis
1.4.1 Symptoms
1.4.2 Medical Diagnosis
1.5 Treatment Options for Peripheral Artery Disease
1.5.1 Percutaneous Trans Luminal Angioplasty (PTA)
1.5.2 Drug-Coated Balloons (DCBs)
1.5.3 Stents
1.5.4 Drug-Eluting Stents (DES)
1.5.5 Arterial Bypass
1.5.6 Atherectomy

2. Global Peripheral Artery Disease Market 
2.1 Global Peripheral Artery Disease Market by Value
2.2 Global Peripheral Artery Disease Prevalence
2.3 Global Peripheral Artery Devices Market
2.3.1 Peripheral Artery Devices Market by Treatment
2.3.2 Drug Eluting Stents Market by Volume
2.3.3 Drug Eluting Stents Market by Geography

3. Regional Peripheral Artery Disease Market 
3.1 The U.S.
3.1.1 The U.S. PAD Diagnosed Cases
3.1.2 The U.S. PAD Interventions and Penetration
3.1.3 The U.S. DCB Procedures and Penetration 

Latest News About Global Wilsons Disease Market: Industry Analysis & Outlook, 2016 - 2020

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Wilson’s disease is a rare disease and is named after Kinnear Wilson who was the first to describe this disorder in 1912. His description terms the disease as a “progressive lenticular degeneration,” a hereditary, fatal neurological disease that is usually accompanied by chronic liver ailment that leads to a condition called cirrhosis. Wilson's disease is a hereditary disorder that leads to unwarranted accumulation of copper in crucial organs such as the liver, brain etc. The patient starts to accumulate copper from birth but diagnosis tends not to occur only in the later ages. The primary signs of Wilson’s disease become prominent usually between the ages of 12 and 23 years.

Wilson’s disease is caused by the mutation of a gene named ATP7B. Absent or reduced function of ATP7B protein leads to reduced elimination of copper into the bile. Wilson’s disease is inherited as an autosomal recessive trait, which means that in order to develop the disease one must inherit two procreations of the defective gene, one from each parent. If a person receives only one abnormal gene from either of the parents, he/she is not likely to get affected by the Wilson’s disease. Wilson’s disease may be difficult to primarily diagnose as the symptoms are alike to other health issues like heavy metal poisoning, hepatitis C, and cerebral palsy.

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The important factors that are anticipated to drive the market include rising prices of chelators in the US, rising attractiveness of orphan drugs market, increasing global healthcare expenditure as well as spending on medicines. The noteworthy trends in the market include falling number of prescriptions for Wilson’s disease, and the development of gene therapy as a potential cure for the disease.

However, the market is confronted by crucial challenges such as under-diagnosis of the disease, lack of safety in treatments, poor compliance to current treatments and unmet efficacy needs.

This report provides a wide-ranging study of global Wilson’s disease market and also its key regional markets such as the US and Europe. Furthermore, market dynamics such as key trends and development; and challenges are analyzed in depth. The global Wilson’s disease industry is highly competitive consisting of several large corporations. The competitive landscape of the respective market, along with the company profiles of the leading players are also discussed in detail.

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Table of Content

1. Market Overview
1.1 Introduction  
1.2 Causes  
1.3 Symptoms  
1.3.1 Hepatic Symptoms  
1.3.2 Neurological Symptoms  
1.3.3 Ophthalmic Symptoms  
1.3.4 Other Symptoms  
1.4 Diagnosis  
1.5 Treatment through Medications  
1.5.1 D-penicillamine  
1.5.2 Trientine  
1.5.3 Zinc Salts  
1.5.4 Ammonium tetrathiomolybdate  
1.5.5 Bis-Choline Tetrathiomolybdate – Decuprate

2. Global Market
2.1 Global Orphan Drugs Market Revenue – Actuals  
2.2 Global Orphan Drugs Market Revenue – Forecast  
2.3 Wilson’s Disease Prevalence by Region  
2.4 Wilson’s Disease Market by Treatment – New Patients  
2.5 Wilson’s Disease Market by Treatment – Experienced Patients  
2.6 Global Decuprate Revenue – Forecast  
2.7 Global Liver Transplantation by Region

Worldwide Analysis Of Fatty Liver Disease - High Degree of First-in-Class Innovation, Dominated by Nuclear Receptor-Targeting NASH Products

Researchmoz added Most up-to-date research on "Worldwide Analysis Of Fatty Liver Disease - High Degree of First-in-Class Innovation, Dominated by Nuclear Receptor-Targeting NASH Products" to its huge collection of research reports.

Fatty liver disease (FLD) comprises a spectrum of chronic liver disorders characterized by excessive lipid accumulation in the liver (steatosis), which may lead to inflammation (steatohepatitis) and fibrosis. It has the potential to progress to end-stage liver diseases such as cirrhosis, liver cancer and liver failure, and is also associated with numerous complications and co-morbidities, including cardiovascular and metabolic diseases. FLD can be divided into non-alcoholic FLD (NAFLD) and alcoholic FLD (AFLD), depending on the patent’s history of alcohol use.

FLD is the most common chronic liver disease in the world, and its global prevalence has increased rapidly in the past several decades. The worldwide prevalence of FLD is estimated at 20–45% in the general population, and up to 90% in obese patients. There is a broad consensus to describe the condition as the hepatic manifestation of metabolic syndrome, and it is closely associated with obesity, diabetes and dyslipidemia. NAFLD has become the main driver of the rapid growth of FLD prevalence, mainly due to the rising prevalence of obesity.

FLD is increasingly recognized as a major global health problem. However, despite this the FLD market is still in its infancy, with no FDA-approved drugs for this indication, and only a limited number of generic drugs approved in non-US markets in recent years.

Due to the increasing health burden of FLD and the lack of therapeutic options, there is a pressing need to develop pharmacological strategies. This is especially the case for patients with steatohepatitis, who are at the greatest risk of developing cirrhosis or liver cancer, which can lead to liver failure. Due to the pathophysiological complexity of FLD and its diverse population, different therapeutic agents are likely to be needed to tackle the lipotoxicity, inflammation and fibrogenesis that drive FLD progression.

FLD has an active pipeline and first-in-class products account for a considerable proportion, which is very promising considering the level of unmet need and lack of approved treatment options. First-in-class innovation is concentrated heavily at the early drug development stages, and prominent first-in-class molecular targets include nuclear receptors, immune mediators, and molecules involved in lipid synthesis. Additionally, the first-in-class targets identified show considerable diversity, reflecting the multifaceted aspects of FLD pathophysiology.

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Scope
FLD comprises a diverse patient population with significant unmet needs

•  What is the pathophysiology of FLD?
•  What are the common co-morbidities and complications?
•  What are the most significant unmet needs within the market?

The FLD pipeline is relatively large and has a high degree of first-in-class innovation

•  Which molecule types and molecular targets are most prominent within the pipeline?
• Which first-in-class targets are most promising?
• How does the ratio of first-in-class targets to first-in-class products differ by stage of development and molecular target class?

The FLD deal landscape shows rising deal volumes and considerable investment opportunities

• Do FLD products attract high deal values?
• Which molecule types and molecular targets dominate the deals landscape?
• Which first-in-class pipeline products have no prior involvement in licensing or co-development deals?

Reasons to buy
This report will allow you to - 

• Appreciate the current clinical and commercial landscapes by considering disease pathogenesis, etiology, epidemiology, symptoms, co-morbidities and complications, and treatment options and algorithms.
• Visualize the composition of the FLD market in terms of dominant classes of therapies. Key unmet needs are identified to allow a competitive understanding of gaps in the market.
• Recognize innovative pipeline trends by analyzing therapies by stage of development, molecule type and molecular target.
• Assess the therapeutic potential of first-in-class targets. Using a proprietary matrix tailored to FLD, all first-in-class targets in the pipeline have been assessed and ranked according to clinical potential. Promising early-stage targets have been further reviewed in greater detail.
• Consider first-in-class pipeline products with no prior involvement in licensing and co-development deals that may represent potential investment opportunities.

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Symptoms Of Chronic Obstructive Pulmonary Disease Including Shortness Of Breath, Wheezing, Chest Tightness, Cough - Global Drug Forecast and Market Analysis to 2025

ResearchMoz presents this most up-to-date research on "Symptoms Of Chronic Obstructive Pulmonary Disease Including Shortness Of Breath, Wheezing, Chest Tightness, Cough - Global Drug Forecast and Market Analysis to 2025".

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by an abnormal inflammatory response and airflow obstruction that is not fully reversible. Chronic airflow limitation is caused by both small airway diseases, such as obstructive bronchiolitis, as well as parenchymal destruction, including emphysema. Research suggests that the pathogenesis of COPD involves both genetic and environmental factors. The fourth leading cause of death in the world, COPD progresses slowly and symptoms, including shortness of breath, wheezing, chest tightness, cough, and increased mucous production, worsen over time. Although it is currently unknown if the damage to the airways and lungs can be reversed, treatments and lifestyle changes can help slow the progress of the disease .

GlobalData estimates the 2015 sales for the COPD market at approximately $9.9 billion across the 8MM, encompassing the US, the five major European Union countries (5EU: France, Germany, Italy, Spain, and UK), Japan, and Australia. Over the course of the 10-year forecast period, the COPD market will grow at a Compound Annual Growth Rate (CAGR) of 3.7% across the 8MM. Each of the 8MM are anticipated to grow significantly, recording CAGRs of 3.7%, 5.2%, 4.3%, and 6.6% across the US, 5EU, Japan, and Australia, respectively. At the end of 2025, the US will account for 77.8% of sales across the 8MM, while the 5EU, Japan, and Australia will account for around 19.2%, 2.4%, and 0.7% of sales, respectively. The higher sales numbers for the US can be attributed to the higher prices of pharmaceuticals and the greater diagnosed prevalence of COPD in the region, as well as the anticipated high annual cost of therapy (ACOT) of GSK’s Nucala and AstraZeneca’s benralizumab in the US market.

Key Questions Answered
How will the COPD market landscape in the 8MM (US, France, Germany, Italy, Spain, UK , Japan, and Australia) change from 2015–2025?
What are the most promising late-stage pipeline drugs in COPD?
How do the clinical and commercial attributes of late-stage pipeline therapies compare with one another, and against existing treatment options?
What are the greatest unmet needs in COPD? Will the pipeline drugs fulfil these needs of the market?
What are the largest opportunities in the COPD landscape?

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Scope
Overview of COPD, including epidemiology (mMRC and CAT patient population), etiology, pathophysiology, symptoms, diagnosis, and current management strategies.
Topline COPD market revenue from 2015–2025. ACOT and major pipeline product sales in this forecast period are included.
Key topics covered include current treatment options, unmet needs and opportunities, and the drivers and barriers affecting COPD therapeutics sales in the 8MM.
Pipeline analysis: comprehensive data split across different phases, emerging novel trends under development, synopses of innovative early-stage projects, and detailed analysis of late-stage pipeline products.
Analysis of the current and future market competition in the global COPD therapeutics market. Insightful review of the key industry drivers, restraints, and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy
The report will enable you to:
Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
Develop business strategies by understanding the trends shaping and driving the global COPD therapeutics market.
Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the COPD therapeutics market in the future.
Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.

Companies mentioned
AstraZeneca
Boehringer Ingelheim
Chiesi
GSK
Novartis
Sunovion

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Functioning Of Primary Immunodeficiency Disease In Global Market During The Forecast Period 2014 - 2020

Researchmoz added Most up-to-date research on "Functioning Of Primary Immunodeficiency Disease In Global Market During The Forecast Period 2014 - 2020" to its huge collection of research reports.

Abnormal functioning of immune system due to lack of necessary antibodies or lack of normal functioning of present antibodies is referred as primary immunodeficiency disease. Immunodeficiency is referred as primary immunodeficiency when any disease, environmental exposure to toxins or drug treatment is not the cause of the disease. Primary immunodeficiency disease is also referred as primary immune disorder or primary immunodeficiency disorder. Approximately one in every 500 people is observed to have primary immunodeficiency disease. 

Primary immunodeficiency disease is a genetic disorder. Signs and symptoms of primary immunodeficiency disorder include recurrent bronchitis, pneumonia, meningitis, and ear infection. In addition, sinus infection, blood infection, skin infection, infection of internal organs, inflammation, and delayed development and growth are also observed. In addition, loss of appetite, diarrhea, nausea, cramping, digestive problems, blood disorders including, anemia, and low platelet count are also observed in some cases. Immunodeficiency disorder is commonly diagnosed in infants. However, mild form of primary immunodeficiency may not be diagnosed until adulthood. Based on the types, the global primary immunodeficiency disorder market is segmented as follows:

• B cell (antibody) deficiencies
• T cell deficiencies
• Combination B and T cell deficiencies
• Defective phagocytes
• Combination B and T cell deficiencies
• Complement deficiencies
• Unknown (idiopathic)

Based on the diagnostic tests, global primary immunodeficiency disorder market is segmented as follows:

• Blood Tests
• Prenatal Testing
• DNA Testing
• Tissue and Placental Sample Testing 
• Others

Based on the treatment, global primary immunodeficiency disorder market is segmented as follows:

• Antibiotics for Treating Symptoms
• Treatment to Boost the Immune System
  • Immunoglobulin Therapy
  • Gamma Interferon Therapy
  • Growth Factors

• Treatment to Cure Primary Immunodeficiency
• Stem Cell Transplantation

Geographically, the global primary immunodeficiency disorder market is segmented as North America, Europe, Asia-Pacific, and Rest of the World (RoW) regions. Presently, North America is dominating the global primary immunodeficiency disorders market. Europe is the second largest market in the overall primary immunodeficiency disease market. Exceptionally developed healthcare infrastructure, reimbursement coverage, higher healthcare spending, availability of advanced healthcare technology, and high rate of awareness about primary immunodeficiency disease are few of the major factors that are driving the growth of the primary immunodeficiency disease market in North America and Europe. Asia-Pacific is a lucrative market for primary immunodeficiency diseases market. 

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Rapidly developing healthcare infrastructure, increasing disposable income and government initiatives to improve healthcare industry in respective country on the ground of rapidly growing medical tourism industry are some of the factors that are driving the growth of primary immunodeficiency disease market in Asia-Pacific. China and India are expected to grow swiftly owing to rapidly developing medical tourism industry in these countries. Apart from China and India, Japan is expected to contribute in the growth of the primary immunodeficiency disease market in Asia due to increased focus of Japanese government to offer improved and advanced healthcare facilities to Japanese citizens. Mexico, Brazil, and Argentina are the countries in the Rest of the World (RoW) region that are expected to demonstrate faster growth in the primary immunodeficiency market than African countries. Middle Eastern countries along with rest of the Latin American countries are expected to be second fastest growing markets for the primary immunodeficiency disease in the Rest of the World (RoW) region. 

This research report analyzes this market on the basis of its market segments, major geographies, and current market trends. This report provides comprehensive analysis of 

• Market growth drivers 
• Factors limiting market growth
• Current market trends 
• Market structure
• Market projections for upcoming years 

This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis. 

Reasons for Buying this Report

• This report provides pin-point analysis for changing competitive dynamics
• It provides a forward looking perspective on different factors driving or restraining market growth 
• It provides a six-year forecast assessed on the basis of how the market is predicted to grow 
• It helps in understanding the key product segments and their future
• It provides pin point analysis of changing competition dynamics and keeps you ahead of competitors

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